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Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.
Ramirez J, Lectez B, Osinalde N, Sivá M, Elu N, Aloria K, Procházková M, Perez C, Martínez-Hernández J, Barrio R, Grantz Šašková K, Arizmendi JM and Mayor U*
Human Molecular Genetics (2018) 27(11):1955-1971.
doi: 10.1093/hmg/ddy103.
PMID: 29788202
Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer.
Valcarcel-Jimenez L, Macchia A, Martín-Martín N, Cortazar AR, Schaub-Clerigué A, Pujana-Vaquerizo M, Fernández-Ruiz S, Lacasa-Viscasillas I, Santos-Martin A, Loizaga-Iriarte A, Unda-Urzaiz M, Hermanova I, Astobiza I, Graupera M, Starkova J, Sutherland J, Barrio R, Aransay AM, Carracedo A, Torrano V.*
Cell Death Dis. (2018) 9(10):1041.
doi: 10.1038/s41419-018-1096-6.
PMID: 30310055
Impaired proteostasis in rare neurological diseases.
Osinalde N, Duarri A, Ramirez J, Barrio R, de Nanclares GP, Mayor U.*
Semin Cell Dev Biol. (2018) pii: S1084-9521(18)30161-7.
doi: 10.1016/j.semcdb.2018.10.007.
PMID: 30355526
Putting the Stress on UFM1 (Ubiquitin-Fold Modifier 1).
Circ Heart Fail. (2018) 11(10):e005455.
doi: 10.1161/CIRCHEARTFAILURE.118.005455.
PMID: 30354403
Cluster Locator, online analysis and visualization of gene clustering.
Pazos Obregón F*, Soto P, Lavín JL, Cortázar AR, Barrio R, Aransay AM, Cantera R.
Bioinformatics. 2018 Apr 25.
doi: 10.1093/bioinformatics/bty336.s
PMID: 29701747
Truncated SALL1 impedes primary cilia function in Townes-Brocks Syndrome.
Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurdsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD*, Barrio R*
The American Journal of Human Genetics (2018), 102, 249–265.
doi: 10.1016/j.ajhg.2017.12.017.
PMID: 29395072
PPARδ elicits ligand-independent repression of Trefoil Factor Family to limit prostate cancer growth.
Martín-Martín N, Arreal L, Fernández-Ruiz S, Castillo-Martin M, Cortazar AR, Torrano V, Zúñiga-García P, Zabala-Letona A, Ugalde-Olano A, Loizaga-Iriarte A, Unda M, Valcárcel-Jiménez L, Arruabarrena-Aristorena A, Piva M, Sánchez-Mosquera P, Aransay AM, Barrio R, Sutherland JD, Carracedo A*
Cancer Research (2018) 78(2):399-409.
doi: 10.1158/0008-5472.CAN-17-0908.
PMID: 29187400
Drosophila melanogaster White Mutant w1118 undergo retinal degeneration
Ferreiro MJ*, Pérez C, Ruiz S, Marchesano M, Ruiz S, Caputi A, Aguilera P, Barrio R, Cantera R*.
Frontiers in Neuroscience (2018) 11:732.
doi: 10.3389/fnins.2017.00732.
PMID: 29354028
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.
Zabala-Letona A, Arruabarrena-Aristorena A, Martín-Martín N, Fernandez-Ruiz S, Sutherland JD... Barrio R, Macarulla T, Mato JM, Martinez-Chantar ML, Cordon-Cardo C, Aransay AM, Marks K, Baselga J, Tabernero J, Nuciforo P, Manning BD, Marjon K, Carracedo A*.
Nature (2017) 547(7661): 109-113.
doi: 10.1038/nature22964
PMID: 28658205
The immunosuppressive effect of the tick salivary protein, Salp15, is persistent and has long-term effects in a murine model of hematopoietic transplant.
Tomás-Cortazar J, Martín-Ruiz I, Barriales D, Pascual-Itoiz MA, Gutierrez de Juan V, Caro-Maldonado A, Merino N, Marina A, Blanco F, Sutherland JD, Barrio R, Rojas A, Martinez-Chantar ML, Carracedo A, Simó C, García-Cañas V, Abecia L, Lavín JL, Aransay AM, Rodríguez H, Anguita J*
Scientific Reports (2017) 7(1):10740.
doi: 10.1038/s41598-017-11354-2
PMID: 28878331